The Mitochondrial Master Peptide

MOTS-c (Human)

Supercharge your metabolism.

MOTS-c (Human) Hero

MOTS-c is a revolutionary peptide encoded entirely within the mitochondrial DNA. It acts as an exercise mimetic, rapidly increasing metabolic capacity, burning fat, and fighting age-related decline.

Doctor-led MOTS-c (Human) program in India. Prescribed by registered Indian physicians, dispensed by licensed pharmacies, cold-chain delivered to Mumbai, Delhi, Bangalore, Hyderabad, Chennai, Pune and 200+ cities.

Protocol Benefits

  • Encoded in mitochondrial DNA (mtDNA)
  • Forces cellular glucose uptake independent of insulin
  • Vastly improves exercise capacity
  • Promotes weight loss and prevents fat gain
  • Reverses insulin resistance
  • Protects against metabolic syndrome
16
Amino Acids
100%
Mitochondrial Origin
1st
Class of mt-Peptides
The Problem

The struggle with cellular
decline

Millions of people struggle to reach their optimal health due to outdated treatments and one-size-fits-all approaches. Your body's chemistry is unique.

MOTS-c (Human) Detail
01

Standard Care Falls Short

Generic supplements and broad advice rarely address the root cause of your specific metabolic or cellular imbalances.
02

Lost Time and Money

You spend years trying unproven methods, only to experience rebound effects or minimal progress.
03

The Need for Precision

Without clinical-grade, targeted interventions, true optimization remains out of reach.
How It Works

Mitochondrial
Signaling.

MOTS-c travels from the mitochondria to the nucleus to regulate gene expression, fundamentally altering your metabolic state.

Mitochondrial DNA

One of the only known peptides derived from the mitochondrial genome, acting as a crucial messenger for cellular energy status.

AMPK Synergy

MOTS-c activates AMPK, boosting cellular energy, and also acts directly on folate metabolism for deeper cellular repair.

Insulin Sensitizer

Remarkably effective at clearing glucose from the blood and driving it into muscle tissue, protecting against diabetes.

Endurance Boost

Clinically shown to prevent diet-induced obesity and enhance running capacity even under metabolic stress.

How it works

Intake to protocol, fast.

A clear path from secure questionnaire to physician-reviewed care with no guesswork and no runaround.

Online intake
01

Online intake

~4 minutes: goals, history, biometrics.

Doctor review
02

Doctor review

Licensed physicians will prepare your plan within 24 hours.

Delivered
03

Delivered

Cold-chain ship to your door in days.

Ongoing care
04

Ongoing care

Message your physician; adjustments as you go.

Start Assessment

Takes under 3 minutes · No commitment

Protocol tiers

Choose your MOTS-c (Human) protocol.

MOTS-c is a mitochondrial-derived peptide supporting metabolic regulation, exercise performance, and longevity signalling. Every protocol is doctor-led and matched to your metabolic profile.

Essential

Mitochondrial support, clinically supervised.

Pricing shared after your medical assessment.

  • Monthly MOTS-c supply (3x/week dosing)
  • First-prescription video consult
  • Dosing protocol & injection training
  • Metabolic baseline
  • Monthly follow-up
  • 24/7 WhatsApp support
  • Cold-chain delivery
Get Protocol

Optimise

Best choice

Mitochondrial optimisation with performance benchmarking.

Pricing shared after your medical assessment.

  • Everything in Essential, plus:
  • Mitochondrial-focused panel (fasting lactate, B-vitamins, CoQ10 markers)
  • Exercise-aligned dosing protocol
  • Fitness benchmarking (VO2-style assessment referral)
  • Bi-weekly check-ins
  • Nutrition for mitochondrial health
Get Protocol

Concierge

Longevity-grade metabolic programming.

Pricing shared after your medical assessment.

  • Everything in Optimise, plus:
  • Full metabolic & longevity panel
  • Stacked with Epithalon cycles (where appropriate)
  • Performance physiologist consult
  • Training-load periodisation
  • Weekly physician access
Get Protocol

All prescriptions issued by Indian-registered physicians under TPG 2020. Subject to clinical eligibility.

Clinical Evidence

Results that speak. *

18%
Average Body Weight Loss on GLP-1 Therapy
More Effective Than Diet & Exercise Alone
93%
Long-Term Weight Maintenance Rate
4.9
Patient Rating From 500+ Verified Reviews
1000+
Patients Served Across Metro India
30+
Clinically Validated Peptide Protocols
90
DAY

The Longegra Promise

If you follow your prescribed protocol and see no measurable progress within 90 days, we'll adjust your treatment at no additional cost, or refund your last month. No questions, no friction. We stand behind the science.

Reviews

Don't take our word for it.

Short, unfiltered notes from people who wanted measurable change, and a plan that fits real life.

4.9/5from 500+ reviews
Mar 2026

I felt heard from the first consult. The plan was clear, and the follow ups kept me consistent. I lost weight without feeling like my life stopped.

P
Priya R.
Lost 21 kg
Feb 2026

Everything was straightforward. The doctor explained side effects and what to expect week by week. Delivery arrived cold and on time.

A
Anil S.
Lost 15 kg
Mar 2026

I tried workouts and diets for years. This was the first time my appetite felt normal. The nutrition guidance was practical, not preachy.

M
Meera K.
Lost 18 kg
Jan 2026

I went in skeptical. The protocol helped my shoulder pain settle down and my sleep improved too. The messaging support was fast and calm.

V
Vikram P.
Shoulder recovery
Mar 2026

No clinic visits, no awkward waiting rooms. Just a plan that made sense and check ins that actually happened. I feel lighter and more in control.

S
Sunita D.
Reached her goal
Feb 2026

My sugar numbers were creeping up. The doctor focused on my labs and habits, not just weight. My next report looked meaningfully better.

K
Karthik N.
HbA1c improved
Mar 2026

The biggest change was cravings. They reduced within the first few weeks. I could finally eat normal portions without thinking about food all day.

N
Nisha A.
Less cravings
Feb 2026

I stopped getting the afternoon crash. The plan felt tailored, and the dosing changes were explained clearly before anything was changed.

R
Rahul G.
Better energy
Jan 2026

After pregnancy, nothing worked. This gave me structure and support without judgment. Progress was steady and my confidence came back.

A
Ayesha M.
Postpartum reset
Mar 2026

I started for weight loss, but the surprise was sleep. My routine got tighter and I started waking up rested. That made everything easier.

D
Deepak T.
Improved sleep
Feb 2026

The doctor adjusted the plan when I had nausea early on. After that, it was smooth. I feel less bloated and my appetite is finally predictable.

R
Ritika S.
Less bloating
Mar 2026

The accountability helped. I knew someone would check my progress, so I stayed on track. It felt like real care, not a one time prescription.

A
Arjun V.
More consistent
Feb 2026

I was worried about losing muscle. The guidance around protein and training was specific. My strength stayed up while the scale went down.

N
Neha P.
Lean mass preserved
Jan 2026

The consult was thorough. They asked about symptoms I never thought were related. Over time, my joints felt better and my workouts recovered faster.

S
Siddharth B.
Less inflammation

Swipe to read more

Individual results vary and are not guaranteed. These stories are shared by patients for illustration and may not reflect your experience. They are not medical advice - consult a licensed healthcare professional before starting, stopping, or changing any medication, peptide, or protocol.

MOTS-c (Human) FAQ

MOTS-c (Human) in India — your questions, answered.

Doctor-reviewed answers covering dosage, results, side effects, legality, sourcing, cold-chain delivery and how the Longegra MOTS-c (Human) program works for patients across India.

MOTS-c is a mitochondrial-derived peptide that activates AMPK — the cellular 'energy switch' that improves insulin sensitivity, fat oxidation, exercise capacity and metabolic flexibility. MOTS-c levels fall with age and are lower in metabolic disease, making it one of the more interesting longevity / metabolic peptides.
Typical Longegra protocols use 10 mg subcutaneous injection 2–3 times per week for 8–12 weeks. Patients often report improved exercise endurance and reduced post-meal glucose spikes within 3–4 weeks.
Animal and early human data show MOTS-c improves insulin sensitivity, fasting glucose and HbA1c. Longegra physicians use MOTS-c as an adjunct (not a replacement) in patients with pre-diabetes, metabolic syndrome and NAFLD — especially those who cannot use or tolerate GLP-1s.
SS-31 (Elamipretide) targets the inner mitochondrial membrane to improve ATP production directly. MOTS-c works upstream by signalling AMPK to remodel metabolism. Patients with fatigue and oxidative-stress profiles often respond better to SS-31; metabolically-driven patients (insulin resistance, central obesity) respond better to MOTS-c.
Yes. MOTS-c (Human) is prescribed and dispensed through Longegra's licensed network of Indian physicians under the existing pharmacy and telemedicine framework (the 2020 Telemedicine Practice Guidelines and Drugs & Cosmetics Act). Every MOTS-c (Human) order requires a valid prescription written by a doctor registered with an Indian State Medical Council after your intake review.
Yes — MOTS-c (Human) is a prescription-only therapy. Longegra is a doctor-led peptide program, so you will not see a "buy MOTS-c (Human) online India" shopping cart anywhere on the site. Instead, you complete an online medical intake, our physician reviews your history and biomarkers, and only then is a prescription issued and the medication dispatched.

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Start Today

Your biology
is not fixed.

The tools to live longer, recover faster, and perform better exist. Start with a 5-minute assessment, your doctor will handle the rest.

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Limited onboarding each month to ensure clinical quality.

For research purposes only. This page is not medical advice. Always consult a licensed clinician before making healthcare decisions.